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Station 10 of 40 • Internal Medicine / Surgery • Original OSCE Practice

Diabetic Foot Infection

Focused NAC OSCE station for a patient with diabetes presenting with a painful infected foot ulcer. Practise urgent assessment, vascular/neurologic screening, osteomyelitis risk, management, and safety-net communication.

Door Prompt

You are a junior physician in an urgent care clinic. A 58-year-old man with type 2 diabetes presents with a painful wound on the bottom of his right foot. He noticed increasing redness and drainage over the last 3 days.

Your tasks:

  1. Take a focused history.
  2. Explain the key physical examination you would perform.
  3. Discuss the most likely diagnosis and important differential diagnoses.
  4. Outline initial investigations and management.
  5. Address the patient’s concerns and provide safety-net advice.
AssessmentFocused diabetic foot, infection severity, vascular status, neuropathy, red flags.
ManagementDisposition, cultures, imaging, antibiotics, wound care, off-loading, specialist referral.
CommunicationPlain-language explanation, shared decisions, warning signs, diabetes foot-care education.
Patient Opening Statement

“Doctor, I have diabetes and this sore under my foot is getting worse. It smells bad and I’m worried I might lose my foot.”

Focused History Checklist
  • Presenting wound: onset, location, trauma/foreign body, footwear injury, progression, pain, swelling, erythema, warmth, purulent drainage, odour, bleeding.
  • Infection severity: fever, chills, rigors, malaise, confusion, tachycardia symptoms, rapidly spreading redness, severe pain, bullae, skin necrosis, crepitus.
  • Osteomyelitis risk: deep ulcer, visible bone, chronic non-healing ulcer, previous ulcers, previous osteomyelitis, previous amputation.
  • Peripheral vascular disease: claudication, rest pain, cold foot, colour change, non-healing wounds, smoking history.
  • Neuropathy: numbness, burning, reduced protective sensation, unrecognized injuries.
  • Diabetes history: duration, recent glycemic control, home glucose readings, medications including insulin, adherence, hypoglycemia, complications.
  • Comorbidities: chronic kidney disease, coronary artery disease, stroke, peripheral arterial disease, immunosuppression.
  • Medication and allergy review: antibiotics, anticoagulants, steroids, SGLT2 inhibitors, drug allergies.
  • Functional and social context: ability to walk, work demands, home supports, access to wound care, financial/footwear barriers.
Key Physical Examination to Verbalize
  • Vital signs and general status: temperature, heart rate, blood pressure, respiratory rate, oxygen saturation, mental status, hydration.
  • Foot inspection: ulcer site, size, depth, edges, drainage, odour, surrounding cellulitis, fluctuance, necrosis, gangrene, callus, deformity, pressure areas.
  • Probe-to-bone assessment: if appropriate and with sterile technique, assess whether bone can be contacted through the ulcer.
  • Neurovascular exam: dorsalis pedis/posterior tibial pulses, capillary refill, skin temperature, colour, ankle-brachial index if available, monofilament sensation, vibration/proprioception.
  • Musculoskeletal exam: swelling, tenderness, range of motion, Charcot-type deformity, signs of deep abscess or septic joint.
  • Systemic exam: cardiac/respiratory assessment if septic or high-risk; examine other foot for ulcers and footwear fit.
Expected Diagnosis and Differential Diagnosis
DiagnosisWhy it mattersClues
Diabetic foot infection Most likely diagnosis; requires severity assessment, cultures when appropriate, antibiotics, wound care, off-loading, and close follow-up or admission. Diabetes, plantar ulcer, increasing erythema, drainage, odour, swelling, pain or reduced sensation.
Osteomyelitis Needs imaging, inflammatory markers, specialist input, prolonged therapy and sometimes surgical debridement. Deep or chronic ulcer, probe-to-bone positive, elevated inflammatory markers, bony changes on imaging.
Peripheral arterial disease / ischemic ulcer Antibiotics alone will fail if perfusion is poor; vascular assessment is essential. Reduced pulses, cool foot, delayed capillary refill, claudication, rest pain, gangrene.
Necrotizing soft tissue infection Surgical emergency. Rapid progression, severe pain out of proportion, systemic toxicity, bullae, necrosis, crepitus.
Charcot neuroarthropathy Can mimic infection and causes deformity/ulcer risk. Warm swollen foot, neuropathy, relatively little pain, deformity, intact or variable pulses.
Investigations
  • Bedside: capillary glucose, vital signs, assess for sepsis, consider ketones if very unwell or hyperglycemic.
  • Laboratory: CBC, electrolytes/creatinine, CRP/ESR, glucose/A1c if not recent; blood cultures if febrile or systemically unwell.
  • Microbiology: deep tissue culture after cleansing/debridement if infected. Avoid superficial swab if possible because it may reflect colonization.
  • Imaging: plain X-ray of foot for gas, foreign body, bony destruction, deformity; MRI if osteomyelitis or deep abscess is suspected and diagnosis remains uncertain.
  • Vascular assessment: pulses, ankle-brachial index/toe pressures if available; vascular imaging/referral if ischemia suspected.
Initial Management Plan
  • Disposition first: admit urgently if systemic toxicity, sepsis, rapidly progressive infection, necrosis/gangrene, suspected necrotizing infection, deep abscess, severe ischemia, inability to walk safely, poor home support, or failure of outpatient therapy.
  • Urgent referral: involve wound care/podiatry, infectious disease, orthopedics/general surgery, and vascular surgery when deep infection, osteomyelitis, abscess, gangrene, or ischemia is suspected.
  • Antibiotics: start empiric antibiotics based on severity, local guidance, allergy history, renal function, and MRSA/Pseudomonas risk; narrow once cultures return.
  • Source control: debridement of devitalized tissue when appropriate; urgent surgical assessment if abscess, necrosis, gas, or compartment/necrotizing features.
  • Off-loading: reduce pressure on the ulcer with appropriate footwear, boot, crutches, or total contact casting if appropriate under specialist supervision.
  • Wound care: cleanse, dress, document size/depth, arrange regular wound review.
  • Diabetes management: optimize glucose, review medications, hydration, renal function, nutrition, smoking cessation, and cardiovascular risk factors.
  • Follow-up: mild outpatient cases require close reassessment, usually within 24–72 hours depending on severity and local pathway.
Communication Points
  • Acknowledge fear: “I understand why you are worried about losing your foot. The goal is to treat this early and protect the foot.”
  • Explain diagnosis clearly: diabetes can reduce sensation and blood flow, allowing wounds to worsen before they are noticed.
  • Explain urgency without alarm: worsening redness, drainage, fever, or poor circulation can become serious quickly.
  • Use shared decision-making: discuss need for imaging, antibiotics, wound care, and possible hospital referral depending on severity.
  • Safety-net: return immediately for fever, chills, spreading redness, increasing pain, black skin, confusion, vomiting, high glucose, or feeling faint.
  • Prevention: daily foot inspection, well-fitting shoes, avoid walking barefoot, prompt care for blisters/cuts, regular diabetes foot checks.
Examiner Oral Questions and Model Answers
  1. What features make this patient unsafe for outpatient treatment?
    Systemic toxicity, sepsis, rapidly spreading cellulitis, deep abscess, necrosis/gangrene, suspected necrotizing infection, severe ischemia, suspected osteomyelitis with unstable condition, inability to care for the wound, or poor follow-up access.
  2. Why is vascular assessment important?
    Poor perfusion delays healing and increases amputation risk. Infection may not improve with antibiotics alone if ischemia is significant.
  3. What is the significance of a positive probe-to-bone test?
    It increases concern for osteomyelitis, especially in a deep infected ulcer, and should prompt imaging and specialist evaluation.
  4. Why should superficial swabs be avoided when possible?
    They may reflect colonizing organisms rather than the true pathogen. A deep tissue specimen after cleaning/debridement is more clinically useful.
  5. What counselling would you give before discharge?
    Explain wound care, off-loading, medication adherence, glucose monitoring, close follow-up, and emergency return precautions for systemic symptoms, spreading infection, black tissue, or worsening pain.
Scoring Checklist
25History
20Exam
30Management
25Communication

High-scoring candidate should:

  • Identify diabetic foot infection and screen for osteomyelitis, ischemia, necrotizing infection, and sepsis.
  • Assess infection severity and decide whether outpatient care or hospital admission is safer.
  • Ask about neuropathy, vascular symptoms, prior ulcers/amputation, renal disease, glycemic control, medications, allergies, and social supports.
  • Verbalize full foot exam including pulses, capillary refill, ulcer depth, drainage, necrosis, monofilament sensation, and contralateral foot check.
  • Order appropriate investigations: glucose, CBC, renal function, CRP/ESR, cultures when indicated, X-ray, MRI if osteomyelitis suspected.
  • Provide management plan: antibiotics, wound care, off-loading, debridement/source control, glycemic optimization, specialist referral, and close follow-up.
  • Communicate empathy, clear risk explanation, and specific safety-net instructions.
Common NAC OSCE Pitfalls
  • Calling it a simple skin infection without assessing depth, perfusion, neuropathy, and systemic severity.
  • Forgetting to ask about previous foot ulcers, amputations, or osteomyelitis.
  • Not checking vascular status before assuming antibiotics alone will solve the problem.
  • Failing to consider necrotizing infection when pain is severe or progression is rapid.
  • Discharging without close reassessment and explicit return precautions.